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The efficacy of Tea Tree Oil.

Summary of Microbiological Testing:

Independent microbiological testing of Australian Tea Tree Oil has shown the minimum inhibitory concentration (MIC) of the oil against a variety of micro-organisms (ie the lowest concentration which will inhibit the growth of a specified micro-organism), several hundred in vitro tests have been conducted using Pharmaceutical Grade Australian Tea Tree Oil.

In summary, it may be concluded that Australian Tea Tree Oil is active against a wide range of micro-organisms including the following:

GRAM POSITIVE BACTERIA
MIC(%v/v)
Staphylococcus aureus
0.5-1.0
Staphylococcus epidermidis
0.5-1.0
Streptococcus pneumoniae
0.25
Streptococcus faecalis
1.0
Streptococcus pyrogenes
1.0
Streptococcus agalactiae
1.25
Propionibacterium acnes
0.75
Beta haemolytic streptococcus
0.5

GRAM NEGATIVE BACTERIA
MIC(%v/v)
Escherichia coli
0.5
Klebsiella pneumoniae
1.0-2.0
Citrobacter spp.
0.5-1.0
Shigella sonnei
0.5
Proteus mirabilis
0.5-1.0
Legionella spp.
0.75-1.0
Pseudomonas aeruginosa
2.0

FUNGI
MIC(%v/v)
Trichophyton mentagrophytes
0.75
Trichophyton rubrum
0.5
Aspergillus niger
1.0
Aspergillus flavus
0.25
Candida albicans
0.5
Microsporum canis
1.0
Microsporum gypseum
1.0
Thermoactinomycetes vulgarus
1.25

U.S.P. XXI Preservative Challenge Test: Pass (0.8%)
   
B.P. (1980) Preservative Challenge Test: Pass (0.8%)
   
Therapeutic Goods Act (TGA) Test:  
TGA Hospital Grade Disinfectant Option A: Pass (pure oil)
TGA Antiseptic Grade Option D: Pass (5% cream)
TGA Hospital Grade Dirty Disinfectant Option B: Pass (pure oil)




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